Effect of body mass index on pharmacokinetics of paclitaxel in patients with early breast cancer

BACKGROUND: Paclitaxel is dosed according to body surface area (BSA) but there is scant information on actual drug exposure in overweight and obese patients. METHODS: Early breast cancer patients receiving paclitaxel at 175 mg/m(2) every 3 weeks, in two BMI groups (normal, 18–24.9 kg/m(2) and overwe...

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Detalles Bibliográficos
Publicado en:Cancer Med
Main Authors: Gota, Vikram, Nookala, Manjunath, Bonda, Avinash, Karanam, Ashwin, Shriyan, Bharati, Kembhavi, Yogesh, Gurjar, Murari, Patil, Anand, Singh, Ashish, Goyal, Navin, Gupta, Sudeep
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2021
Assuntos:
Clinical Cancer Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8086018/
https://ncbi.nlm.nih.gov/pubmed/33826243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3865
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