ADME gene polymorphisms do not influence the pharmacokinetics of docetaxel: Results from a population pharmacokinetic study in Indian cancer patients

BACKGROUND: Pharmacokinetics (PK) of docetaxel is characterized by high inter‐individual variability (IIV). While covariate models that explain the PK variability of docetaxel exist, not much is known about the effects of genetic variations on docetaxel disposition. METHODS: Fifty patients with head...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Med
Egile Nagusiak: Patil, Anand, Shriyan, Bharati, Mehta, Parsshava, Patil, Mrudula, Gurjar, Murari, Nookala, Manjunath, Patil, Vijay, Joshi, Amit, Noronha, Vanita, Prabhash, Kumar, Gota, Vikram
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2021
Gaiak:
Cancer Prevention
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8290241/
https://ncbi.nlm.nih.gov/pubmed/34156160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.4026
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