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Multi-sample measurement of hyperpolarized pyruvate-to-lactate flux in melanoma cells
Hyperpolarized [1-(13)C] pyruvate can be used to examine the metabolic state of cancer cells, highlighting a key metabolic characteristic of cancer: the upregulated metabolic flux to lactate, even in the presence of oxygen (Warburg effect). Thus, the rate constant of (13)C exchange of pyruvate to la...
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| Pubblicato in: | NMR Biomed |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8288443/ https://ncbi.nlm.nih.gov/pubmed/33314422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.4447 |
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