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Real-time quantitative analysis of metabolic flux in live cells using a hyperpolarized micromagnetic resonance spectrometer

Metabolic reprogramming is widely considered a hallmark of cancer, and understanding metabolic dynamics described by the conversion rates or “fluxes” of metabolites can shed light onto biological processes of tumorigenesis and response to therapy. For real-time analysis of metabolic flux in intact c...

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Veröffentlicht in:Sci Adv
Hauptverfasser: Jeong, Sangmoo, Eskandari, Roozbeh, Park, Sun Mi, Alvarez, Julio, Tee, Sui Seng, Weissleder, Ralph, Kharas, Michael G., Lee, Hakho, Keshari, Kayvan R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for the Advancement of Science 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473678/
https://ncbi.nlm.nih.gov/pubmed/28630930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1700341
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