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Hyperpolarized [6-(13)C,(15)N(3)]-Arginine as a Probe for in Vivo Arginase Activity
Alterations in arginase enzyme expression are linked with various diseases and have been shown to support disease progression, thus motivating the development of an imaging probe for this enzymatic target. (13)C-enriched arginine can be used as a hyperpolarized (HP) magnetic resonance (MR) probe for...
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| Publicado en: | ACS Chem Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6474818/ https://ncbi.nlm.nih.gov/pubmed/30893552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b01044 |
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