Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease

SARS-CoV-2 is a coronavirus that emerged in 2019 and rapidly spread across the world causing a deadly pandemic with tremendous social and economic costs. Healthcare systems worldwide are under great pressure, and there is an urgent need for effective antiviral treatments. The only currently approved...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Canal, Berta, McClure, Allison W., Curran, Joseph F., Wu, Mary, Ulferts, Rachel, Weissmann, Florian, Zeng, Jingkun, Bertolin, Agustina P., Milligan, Jennifer C., Basu, Souradeep, Drury, Lucy S., Deegan, Tom D., Fujisawa, Ryo, Roberts, Emma L., Basier, Clovis, Labib, Karim, Beale, Rupert, Howell, Michael, Diffley, John F.X.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2021
Assuntos:
Biochemical Techniques & Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8286829/
https://ncbi.nlm.nih.gov/pubmed/34198326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20210198
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