Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease

SARS-CoV-2 is a coronavirus that emerged in 2019 and rapidly spread across the world causing a deadly pandemic with tremendous social and economic costs. Healthcare systems worldwide are under great pressure, and there is an urgent need for effective antiviral treatments. The only currently approved...

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Dettagli Bibliografici
Pubblicato in:Biochem J
Autori principali: Canal, Berta, McClure, Allison W., Curran, Joseph F., Wu, Mary, Ulferts, Rachel, Weissmann, Florian, Zeng, Jingkun, Bertolin, Agustina P., Milligan, Jennifer C., Basu, Souradeep, Drury, Lucy S., Deegan, Tom D., Fujisawa, Ryo, Roberts, Emma L., Basier, Clovis, Labib, Karim, Beale, Rupert, Howell, Michael, Diffley, John F.X.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2021
Soggetti:
Biochemical Techniques & Resources
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8286829/
https://ncbi.nlm.nih.gov/pubmed/34198326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20210198
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