Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp15 endoribonuclease

SARS-CoV-2 is responsible for COVID-19, a human disease that has caused over 2 million deaths, stretched health systems to near-breaking point and endangered economies of countries and families around the world. Antiviral treatments to combat COVID-19 are currently lacking. Remdesivir, the only anti...

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Bibliographic Details
Published in:Biochem J
Main Authors: Canal, Berta, Fujisawa, Ryo, McClure, Allison W., Deegan, Tom D., Wu, Mary, Ulferts, Rachel, Weissmann, Florian, Drury, Lucy S., Bertolin, Agustina P., Zeng, Jingkun, Beale, Rupert, Howell, Michael, Labib, Karim, Diffley, John F.X.
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2021
Subjects:
Biochemical Techniques & Resources
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8286823/
https://ncbi.nlm.nih.gov/pubmed/34198324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20210199
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