Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp12/7/8 RNA-dependent RNA polymerase

The coronavirus disease 2019 (COVID-19) global pandemic has turned into the largest public health and economic crisis in recent history impacting virtually all sectors of society. There is a need for effective therapeutics to battle the ongoing pandemic. Repurposing existing drugs with known pharmac...

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Vydáno v:Biochem J
Hlavní autoři: Bertolin, Agustina P., Weissmann, Florian, Zeng, Jingkun, Posse, Viktor, Milligan, Jennifer C., Canal, Berta, Ulferts, Rachel, Wu, Mary, Drury, Lucy S., Howell, Michael, Beale, Rupert, Diffley, John F.X.
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2021
Témata:
Biochemical Techniques & Resources
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8286815/
https://ncbi.nlm.nih.gov/pubmed/34198323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20210200
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