Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase

The COVID-19 pandemic has presented itself as one of the most critical public health challenges of the century, with SARS-CoV-2 being the third member of the Coronaviridae family to cause a fatal disease in humans. There is currently only one antiviral compound, remdesivir, that can be used for the...

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Dades bibliogràfiques
Publicat a:Biochem J
Autors principals: Basu, Souradeep, Mak, Tiffany, Ulferts, Rachel, Wu, Mary, Deegan, Tom, Fujisawa, Ryo, Tan, Kang Wei, Lim, Chew Theng, Basier, Clovis, Canal, Berta, Curran, Joseph F., Drury, Lucy S., McClure, Allison W., Roberts, Emma L., Weissmann, Florian, Zeisner, Theresa U., Beale, Rupert, Cowling, Victoria H., Howell, Michael, Labib, Karim, Diffley, John F.X.
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2021
Matèries:
Biochemical Techniques & Resources
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8286817/
https://ncbi.nlm.nih.gov/pubmed/34198328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20210219
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