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Phosphatidylinositol-3 kinase mediates the sweet suppressive effect of leptin in mouse taste cells

Leptin is known to selectively suppress neural and taste cell responses to sweet compounds. The sweet suppressive effect of leptin is mediated by the leptin receptor Ob-Rb, and the ATP-gated K(+) (K(ATP)) channel expressed in some sweet-sensitive, taste receptor family 1 member 3 (T1R3)-positive tas...

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Bibliographic Details
Published in:J Neurochem
Main Authors: Yoshida, Ryusuke, Margolskee, Robert F., Ninomiya, Yuzo
Format: Artigo
Language:Inglês
Published: 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284875/
https://ncbi.nlm.nih.gov/pubmed/33319361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.15268
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