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Leptin Suppresses Mouse Taste Cell Responses to Sweet Compounds

Leptin is known to selectively suppress neural and behavioral responses to sweet-tasting compounds. However, the molecular basis for the effect of leptin on sweet taste is not known. Here, we report that leptin suppresses sweet taste via leptin receptors (Ob-Rb) and K(ATP) channels expressed selecti...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Yoshida, Ryusuke, Noguchi, Kenshi, Shigemura, Noriatsu, Jyotaki, Masafumi, Takahashi, Ichiro, Margolskee, Robert F., Ninomiya, Yuzo
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876703/
https://ncbi.nlm.nih.gov/pubmed/26116698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-1462
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