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Phosphatidylinositol-3 kinase mediates the sweet suppressive effect of leptin in mouse taste cells

Leptin is known to selectively suppress neural and taste cell responses to sweet compounds. The sweet suppressive effect of leptin is mediated by the leptin receptor Ob-Rb, and the ATP-gated K(+) (K(ATP)) channel expressed in some sweet-sensitive, taste receptor family 1 member 3 (T1R3)-positive tas...

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Dades bibliogràfiques
Publicat a:J Neurochem
Autors principals: Yoshida, Ryusuke, Margolskee, Robert F., Ninomiya, Yuzo
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284875/
https://ncbi.nlm.nih.gov/pubmed/33319361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.15268
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