Prediction of combination therapies based on topological modeling of the immune signaling network in multiple sclerosis

BACKGROUND: Multiple sclerosis (MS) is a major health problem, leading to a significant disability and patient suffering. Although chronic activation of the immune system is a hallmark of the disease, its pathogenesis is poorly understood, while current treatments only ameliorate the disease and may...

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Bibliografiske detaljer
Udgivet i:Genome Med
Main Authors: Bernardo-Faura, Marti, Rinas, Melanie, Wirbel, Jakob, Pertsovskaya, Inna, Pliaka, Vicky, Messinis, Dimitris E., Vila, Gemma, Sakellaropoulos, Theodore, Faigle, Wolfgang, Stridh, Pernilla, Behrens, Janina R., Olsson, Tomas, Martin, Roland, Paul, Friedemann, Alexopoulos, Leonidas G., Villoslada, Pablo, Saez-Rodriguez, Julio
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284018/
https://ncbi.nlm.nih.gov/pubmed/34271980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-021-00925-8
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