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A Biologically-Based Computational Approach to Drug Repurposing for Anthrax Infection

Developing drugs to treat the toxic effects of lethal toxin (LT) and edema toxin (ET) produced by B. anthracis is of global interest. We utilized a computational approach to score 474 drugs/compounds for their ability to reverse the toxic effects of anthrax toxins. For each toxin or drug/compound, w...

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Dades bibliogràfiques
Publicat a:Toxins (Basel)
Autors principals: Bai, Jane P. F., Sakellaropoulos, Theodore, Alexopoulos, Leonidas G.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371854/
https://ncbi.nlm.nih.gov/pubmed/28287432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9030099
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