Combined logical and data-driven models for linking signalling pathways to cellular response

BACKGROUND: Signalling pathways are the cornerstone on understanding cell function and predicting cell behavior. Recently, logical models of canonical pathways have been optimised with high-throughput phosphoproteomic data to construct cell-type specific pathways. However, less is known on how signa...

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Détails bibliographiques
Auteurs principaux: Melas, Ioannis N, Mitsos, Alexander, Messinis, Dimitris E, Weiss, Thomas S, Alexopoulos, Leonidas G
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145575/
https://ncbi.nlm.nih.gov/pubmed/21729292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-107
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