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Myeloid Endoplasmic Reticulum Resident Chaperone GP96 Facilitates Inflammation and Steatosis in Alcohol‐Associated Liver Disease

Cellular stress–mediated chaperones are linked to liver macrophage activation and inflammation in alcohol‐associated liver disease (ALD). In this study, we investigate the role of endoplasmic reticulum (ER) resident stress chaperone GP96/HSP90B1/GRP94, paralog of the HSP90 family, in ALD pathogenesi...

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Bibliografiske detaljer
Udgivet i:Hepatol Commun
Main Authors: Ratna, Anuradha, Lim, Arlene, Li, Zihai, Argemi, Josepmaria, Bataller, Ramon, Chiosis, Gabriela, Mandrekar, Pranoti
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8279472/
https://ncbi.nlm.nih.gov/pubmed/34278167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1713
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