Myeloid Endoplasmic Reticulum Resident Chaperone GP96 Facilitates Inflammation and Steatosis in Alcohol‐Associated Liver Disease

Cellular stress–mediated chaperones are linked to liver macrophage activation and inflammation in alcohol‐associated liver disease (ALD). In this study, we investigate the role of endoplasmic reticulum (ER) resident stress chaperone GP96/HSP90B1/GRP94, paralog of the HSP90 family, in ALD pathogenesi...

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Vydáno v:Hepatol Commun
Hlavní autoři: Ratna, Anuradha, Lim, Arlene, Li, Zihai, Argemi, Josepmaria, Bataller, Ramon, Chiosis, Gabriela, Mandrekar, Pranoti
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8279472/
https://ncbi.nlm.nih.gov/pubmed/34278167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1713
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