gp96, an endoplasmic reticulum master chaperone for integrins and Toll-like receptors, selectively regulates early T and B lymphopoiesis

Integrins contribute to lymphopoiesis, whereas Toll-like receptors (TLRs) facilitate the myeloid replenishment during inflammation. The combined role of TLRs and integrin on hematopoiesis remains unclear. gp96 (grp94, HSP90b1) is an endoplasmic reticulum master chaperone for multiple TLRs. We report...

Full description

Saved in:
Bibliographic Details
Main Authors: Staron, Matthew, Yang, Yi, Liu, Bei, Li, Janet, Shen, Yuankai, Zúñiga-Pflücker, Juan Carlos, Aguila, Hector L., Goldschneider, Irving, Li, Zihai
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2010
Subjects:
Hematopoiesis and Stem Cells
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845896/
https://ncbi.nlm.nih.gov/pubmed/19965672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-233031
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items