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Endoplasmic reticulum HSP90b1 (gp96, grp94) optimizes B-cell

Endoplasmic reticulum (ER) unfolded protein response (UPR) plays pivotal roles in both early B-cell development and plasma cell differentiation. As a major ER chaperone to mediate the UPR and a master chaperone for Toll-like receptors (TLRs), HSP90b1 (grp94, gp96) has long been implicated to facilit...

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Bibliografiske detaljer
Main Authors: Liu, Bei, Li, Zihai
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515121/
https://ncbi.nlm.nih.gov/pubmed/18509083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-03-143107
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