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Grp94, the endoplasmic reticulum Hsp90, has a similar solution conformation to cytosolic Hsp90 in the absence of nucleotide

The molecular chaperone, Hsp90, is an essential eukaryotic protein that assists in the maturation and activation of client proteins. Hsp90 function depends upon the binding and hydrolysis of ATP, which causes large conformational rearrangements in the chaperone. Hsp90 is highly conserved from bacter...

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Bibliografske podrobnosti
Main Authors: Krukenberg, Kristin A, Böttcher, Ulrike M K, Southworth, Daniel R, Agard, David A
Format: Artigo
Jezik:Inglês
Izdano: Wiley Subscription Services, Inc., A Wiley Company 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777357/
https://ncbi.nlm.nih.gov/pubmed/19554567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.191
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