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Exogenous misfolded protein oligomers can cross the intestinal barrier and cause a disease phenotype in C. elegans
Misfolded protein oligomers are increasingly recognized as highly cytotoxic agents in a wide range of human disorders associated with protein aggregation. In this study, we assessed the possible uptake and resulting toxic effects of model protein oligomers administered to C. elegans through the cult...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8277765/ https://ncbi.nlm.nih.gov/pubmed/34257326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-93527-8 |
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