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Predictive performance of parent-metabolite population pharmacokinetic models of (S)-ketamine in healthy volunteers
PURPOSE: The recent repurposing of ketamine as treatment for pain and depression has increased the need for accurate population pharmacokinetic (PK) models to inform the design of new clinical trials. Therefore, the objectives of this study were to externally validate available PK models on (S)-(nor...
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| 出版年: | Eur J Clin Pharmacol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer Berlin Heidelberg
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8275530/ https://ncbi.nlm.nih.gov/pubmed/33575848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-021-03104-1 |
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