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Predictive performance of parent-metabolite population pharmacokinetic models of (S)-ketamine in healthy volunteers
PURPOSE: The recent repurposing of ketamine as treatment for pain and depression has increased the need for accurate population pharmacokinetic (PK) models to inform the design of new clinical trials. Therefore, the objectives of this study were to externally validate available PK models on (S)-(nor...
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| Publicat a: | Eur J Clin Pharmacol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer Berlin Heidelberg
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8275530/ https://ncbi.nlm.nih.gov/pubmed/33575848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-021-03104-1 |
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