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Population pharmacokinetic analysis of axitinib in healthy volunteers

AIMS: Axitinib is a potent and selective second generation inhibitor of vascular endothelial growth factor receptors 1, 2 and 3 approved for second line treatment of advanced renal cell carcinoma. The objectives of this analysis were to assess plasma pharmacokinetics and identify covariates that may...

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Bibliographic Details
Main Authors: Garrett, May, Poland, Bill, Brennan, Meghan, Hee, Brian, Pithavala, Yazdi K, Amantea, Michael A
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952722/
https://ncbi.nlm.nih.gov/pubmed/23834452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12206
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