Llwytho...

The interplay of Rac1 activity, ubiquitination and GDI binding and its consequences for endothelial cell spreading

Signaling by the Rho GTPase Rac1 is key to the regulation of cytoskeletal dynamics, cell spreading and adhesion. It is widely accepted that the inactive form of Rac1 is bound by Rho GDI, which prevents Rac1 activation and Rac1-effector interactions. In addition, GDI-bound Rac1 is protected from prot...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Majolée, Jisca, Podieh, Fabienne, Hordijk, Peter L., Kovačević, Igor
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274835/
https://ncbi.nlm.nih.gov/pubmed/34252134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0254386
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!