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Endothelial CD2AP binds the receptor ICAM-1 to control mechanosignaling, leukocyte adhesion and the route of leukocyte diapedesis in vitro

Inflammation is driven by excessive transmigration (diapedesis) of leukocytes from the blood to the tissue across the endothelial cell monolayer that lines blood vessels. Leukocyte adhesion, crawling and transmigration are regulated by clustering of the endothelial mechanosensitive receptor intercel...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Schaefer, Antje, van Duijn, Trynette J., Majolee, Jisca, Burridge, Keith, Hordijk, Peter L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510545/
https://ncbi.nlm.nih.gov/pubmed/28484055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601987
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