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Endothelial CD2AP binds the receptor ICAM-1 to control mechanosignaling, leukocyte adhesion and the route of leukocyte diapedesis in vitro

Inflammation is driven by excessive transmigration (diapedesis) of leukocytes from the blood to the tissue across the endothelial cell monolayer that lines blood vessels. Leukocyte adhesion, crawling and transmigration are regulated by clustering of the endothelial mechanosensitive receptor intercel...

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Publicado en:J Immunol
Autores principales: Schaefer, Antje, van Duijn, Trynette J., Majolee, Jisca, Burridge, Keith, Hordijk, Peter L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510545/
https://ncbi.nlm.nih.gov/pubmed/28484055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601987
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