RhoG regulates endothelial apical cup assembly downstream from ICAM1 engagement and is involved in leukocyte trans-endothelial migration

During trans-endothelial migration (TEM), leukocytes use adhesion receptors such as intercellular adhesion molecule-1 (ICAM1) to adhere to the endothelium. In response to this interaction, the endothelium throws up dynamic membrane protrusions, forming a cup that partially surrounds the adherent leu...

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Bibliographic Details
Main Authors: van Buul, Jaap D., Allingham, Michael J., Samson, Thomas, Meller, Julia, Boulter, Etienne, García-Mata, Rafael, Burridge, Keith
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2007
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064659/
https://ncbi.nlm.nih.gov/pubmed/17875742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200612053
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