Impaired Iron Homeostasis and Haematopoiesis Impacts Inflammation in the Ageing Process in Down Syndrome Dementia

Down syndrome (DS) subjects are more likely to develop the clinical features of Alzheimer’s disease (AD) very early in the disease process due to the additional impact of neuroinflammation and because of activation of innate immunity. Many factors involved in the neuropathology of AD in DS, includin...

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Veröffentlicht in:J Clin Med
Hauptverfasser: Raha-Chowdhury, Ruma, Raha, Animesh Alexander, Henderson, James, Ghaffari, Seyedeh Deniz, Grigorova, Monika, Beresford-Webb, Jessica, Allinson, Kieren, Chakraborty, Subhojit, Holland, Anthony, Zaman, Shahid H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268765/
https://ncbi.nlm.nih.gov/pubmed/34209847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10132909
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