Hepcidin Increases Cytokines in Alzheimer’s Disease and Down’s Syndrome Dementia: Implication of Impaired Iron Homeostasis in Neuroinflammation

The liver-derived hormone hepcidin, a member of the defensin family of antimicrobial peptides, plays an important role in host defense and innate immunity due to its broad antibacterial and antiviral properties. Ferritin, an iron storage protein is often associated with iron deficiency, hypoferritin...

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Détails bibliographiques
Publié dans:Front Aging Neurosci
Auteurs principaux: Raha, Animesh Alexander, Ghaffari, Seyedeh Deniz, Henderson, James, Chakraborty, Subhojit, Allinson, Kieren, Friedland, Robert P., Holland, Anthony, Zaman, Shahid H., Mukaetova-Ladinska, Elizabeta B., Raha-Chowdhury, Ruma
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Neuroscience
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120149/
https://ncbi.nlm.nih.gov/pubmed/33994996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.653591
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