Hepcidin Increases Cytokines in Alzheimer’s Disease and Down’s Syndrome Dementia: Implication of Impaired Iron Homeostasis in Neuroinflammation

The liver-derived hormone hepcidin, a member of the defensin family of antimicrobial peptides, plays an important role in host defense and innate immunity due to its broad antibacterial and antiviral properties. Ferritin, an iron storage protein is often associated with iron deficiency, hypoferritin...

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Veröffentlicht in:Front Aging Neurosci
Hauptverfasser: Raha, Animesh Alexander, Ghaffari, Seyedeh Deniz, Henderson, James, Chakraborty, Subhojit, Allinson, Kieren, Friedland, Robert P., Holland, Anthony, Zaman, Shahid H., Mukaetova-Ladinska, Elizabeta B., Raha-Chowdhury, Ruma
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120149/
https://ncbi.nlm.nih.gov/pubmed/33994996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.653591
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