Hepcidin Increases Cytokines in Alzheimer’s Disease and Down’s Syndrome Dementia: Implication of Impaired Iron Homeostasis in Neuroinflammation

The liver-derived hormone hepcidin, a member of the defensin family of antimicrobial peptides, plays an important role in host defense and innate immunity due to its broad antibacterial and antiviral properties. Ferritin, an iron storage protein is often associated with iron deficiency, hypoferritin...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Raha, Animesh Alexander, Ghaffari, Seyedeh Deniz, Henderson, James, Chakraborty, Subhojit, Allinson, Kieren, Friedland, Robert P., Holland, Anthony, Zaman, Shahid H., Mukaetova-Ladinska, Elizabeta B., Raha-Chowdhury, Ruma
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120149/
https://ncbi.nlm.nih.gov/pubmed/33994996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.653591
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