Impaired Iron Homeostasis and Haematopoiesis Impacts Inflammation in the Ageing Process in Down Syndrome Dementia

Down syndrome (DS) subjects are more likely to develop the clinical features of Alzheimer’s disease (AD) very early in the disease process due to the additional impact of neuroinflammation and because of activation of innate immunity. Many factors involved in the neuropathology of AD in DS, includin...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Raha-Chowdhury, Ruma, Raha, Animesh Alexander, Henderson, James, Ghaffari, Seyedeh Deniz, Grigorova, Monika, Beresford-Webb, Jessica, Allinson, Kieren, Chakraborty, Subhojit, Holland, Anthony, Zaman, Shahid H.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268765/
https://ncbi.nlm.nih.gov/pubmed/34209847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10132909
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