Nephroprotective Effects of Tetramethylpyrazine Nitrone TBN in Diabetic Kidney Disease

Diabetic kidney disease (DKD) is the leading cause of end-stage renal failure, but therapeutic options for nephroprotection are limited. Oxidative stress plays a key role in the pathogenesis of DKD. Our previous studies demonstrated that tetramethylpyrazine nitrone (TBN), a novel nitrone derivative...

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Pubblicato in:Front Pharmacol
Autori principali: Jing, Mei, Cen, Yun, Gao, Fangfang, Wang, Ting, Jiang, Jinxin, Jian, Qianqian, Wu, Liangmiao, Guo, Baojian, Luo, Fangcheng, Zhang, Gaoxiao, Wang, Ying, Xu, Lipeng, Zhang, Zaijun, Sun, Yewei, Wang, Yuqiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264657/
https://ncbi.nlm.nih.gov/pubmed/34248629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.680336
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