Tetramethylpyrazine nitrone activates the BDNF/Akt/CREB pathway to promote post‐ischaemic neuroregeneration and recovery of neurological functions in rats

BACKGROUND AND PURPOSE: Neuronal regeneration from endogenous precursors is an attractive strategy for the treatment of ischaemic stroke. However, most stroke‐generated newborn neurons die over time. Therefore, a drug that is both neuroprotective and pro‐neurogenic may be beneficial after stroke. He...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Zhang, Gaoxiao, Zhang, Tao, Li, Ning, Wu, Liangmiao, Gu, Jianbo, Li, Cuimei, Zhao, Chen, Liu, Wei, Shan, Luchen, Yu, Pei, Yang, Xifei, Tang, Yaohui, Yang, Guo‐Yuan, Wang, Yuqiang, Sun, Yewei, Zhang, Zaijun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773967/
https://ncbi.nlm.nih.gov/pubmed/29161771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14102
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