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Retinol-binding protein 4 mRNA translation in hepatocytes is enhanced by activation of mTORC1

Increased expression of the peptide hormone retinol-binding protein 4 (RBP4) has been implicated in the development of insulin resistance, type 2 diabetes, and visual dysfunction. Prior investigations of the mechanisms that influence RBP4 synthesis have focused solely on changes in mRNA abundance. Y...

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Опубликовано в: :Am J Physiol Endocrinol Metab
Главные авторы: Welles, Jaclyn E., Toro, Allyson L., Sunilkumar, Siddharth, Stevens, Shaunaci A., Purnell, Carson J., Kimball, Scot R., Dennis, Michael D.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260359/
https://ncbi.nlm.nih.gov/pubmed/33284085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00494.2020
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