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Glucagon-dependent suppression of mTORC1 is associated with upregulation of hepatic FGF21 mRNA translation
Fibroblast growth factor 21 (FGF21) is a peptide hormone that acts to enhance insulin sensitivity and reverse many of the metabolic defects associated with consumption of a high-fat diet. Recent studies show that the liver is the primary source of FGF21 in the blood and that hepatic FGF21 expression...
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| Veröffentlicht in: | Am J Physiol Endocrinol Metab |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7468783/ https://ncbi.nlm.nih.gov/pubmed/32421369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00555.2019 |
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