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Glucagon-dependent suppression of mTORC1 is associated with upregulation of hepatic FGF21 mRNA translation

Fibroblast growth factor 21 (FGF21) is a peptide hormone that acts to enhance insulin sensitivity and reverse many of the metabolic defects associated with consumption of a high-fat diet. Recent studies show that the liver is the primary source of FGF21 in the blood and that hepatic FGF21 expression...

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Vydáno v:Am J Physiol Endocrinol Metab
Hlavní autoři: Welles, Jaclyn E., Dennis, Michael D., Jefferson, Leonard S., Kimball, Scot R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7468783/
https://ncbi.nlm.nih.gov/pubmed/32421369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00555.2019
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