GEFT Inhibits Autophagy and Apoptosis in Rhabdomyosarcoma via Activation of the Rac1/Cdc42-mTOR Signaling Pathway

Autophagy and apoptosis are dynamic processes that determine the fate of cells, and regulating these processes can treat cancer. GEFT is highly expressed in rhabdomyosarcoma (RMS), which accelerates the tumorigenicity and metastasis of RMS by activating Rac1/Cdc42 signaling, but the regulatory mecha...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Li, Chunsen, Li, Zhenzhen, Song, Lingxie, Meng, Lian, Xu, Guixuan, Zhang, Haijun, Hu, Jianming, Li, Feng, Liu, Chunxia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8252888/
https://ncbi.nlm.nih.gov/pubmed/34221974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.656608
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