GEFT Inhibits Autophagy and Apoptosis in Rhabdomyosarcoma via Activation of the Rac1/Cdc42-mTOR Signaling Pathway

Autophagy and apoptosis are dynamic processes that determine the fate of cells, and regulating these processes can treat cancer. GEFT is highly expressed in rhabdomyosarcoma (RMS), which accelerates the tumorigenicity and metastasis of RMS by activating Rac1/Cdc42 signaling, but the regulatory mecha...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Li, Chunsen, Li, Zhenzhen, Song, Lingxie, Meng, Lian, Xu, Guixuan, Zhang, Haijun, Hu, Jianming, Li, Feng, Liu, Chunxia
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8252888/
https://ncbi.nlm.nih.gov/pubmed/34221974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.656608
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