GEFT Inhibits Autophagy and Apoptosis in Rhabdomyosarcoma via Activation of the Rac1/Cdc42-mTOR Signaling Pathway

Autophagy and apoptosis are dynamic processes that determine the fate of cells, and regulating these processes can treat cancer. GEFT is highly expressed in rhabdomyosarcoma (RMS), which accelerates the tumorigenicity and metastasis of RMS by activating Rac1/Cdc42 signaling, but the regulatory mecha...

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Detalles Bibliográficos
Publicado en:Front Oncol
Autores principales: Li, Chunsen, Li, Zhenzhen, Song, Lingxie, Meng, Lian, Xu, Guixuan, Zhang, Haijun, Hu, Jianming, Li, Feng, Liu, Chunxia
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8252888/
https://ncbi.nlm.nih.gov/pubmed/34221974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.656608
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