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Selective, pH‐Dependent Colorimetric and Fluorimetric Detection of Quadruplex DNA with 4‐Dimethylamino(phenyl)‐Substituted Berberine Derivatives

The 9‐ and 12‐dimethylaminophenyl‐substituted berberine derivatives 3 a and 3 b were readily synthesized by Suzuki‐Miyaura reactions and shown to be useful fluorescent probes for the optical detection of quadruplex DNA (G4‐DNA). Their association with the nucleic acids was investigated by spectromet...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Wickhorst, Peter Jonas, Ihmels, Heiko
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8252107/
https://ncbi.nlm.nih.gov/pubmed/33855748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202100297
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