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Selective, pH‐Dependent Colorimetric and Fluorimetric Detection of Quadruplex DNA with 4‐Dimethylamino(phenyl)‐Substituted Berberine Derivatives

The 9‐ and 12‐dimethylaminophenyl‐substituted berberine derivatives 3 a and 3 b were readily synthesized by Suzuki‐Miyaura reactions and shown to be useful fluorescent probes for the optical detection of quadruplex DNA (G4‐DNA). Their association with the nucleic acids was investigated by spectromet...

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Vydáno v:Chemistry
Hlavní autoři: Wickhorst, Peter Jonas, Ihmels, Heiko
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8252107/
https://ncbi.nlm.nih.gov/pubmed/33855748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202100297
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