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Synthesis and investigation of quadruplex-DNA-binding, 9-O-substituted berberine derivatives
A small series of five novel berberine derivatives was synthesized by the Cu-catalyzed click reaction of 9-propargyladenine with 9-O-(azidoalkyl)berberine derivatives. The association of the resulting berberine–adenine conjugates with representative quadruplex-forming oligonucleotides 22AG dA(G(3)TT...
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| Publicado no: | Beilstein J Org Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Beilstein-Institut
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7684686/ https://ncbi.nlm.nih.gov/pubmed/33281983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.16.230 |
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