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Synthesis and Anticancer Activity of Novel 9-O-Substituted Berberine Derivatives

Berberine is a bioactive isoquinoline alkaloid derived from many plants. Although berberine has been shown to inhibit growth and induce apoptosis of several tumor cell lines, its poor absorption and moderate activity hamper its full therapeutic potential. Here, we describe the synthesis of a series...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Milata, Viktor, Svedova, Alexandra, Barbierikova, Zuzana, Holubkova, Eva, Cipakova, Ingrid, Cholujova, Dana, Jakubikova, Jana, Panik, Miroslav, Jantova, Sona, Brezova, Vlasta, Cipak, Lubos
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6539820/
https://ncbi.nlm.nih.gov/pubmed/31052469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20092169
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