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Synthesis and Anticancer Activity of Novel 9-O-Substituted Berberine Derivatives

Berberine is a bioactive isoquinoline alkaloid derived from many plants. Although berberine has been shown to inhibit growth and induce apoptosis of several tumor cell lines, its poor absorption and moderate activity hamper its full therapeutic potential. Here, we describe the synthesis of a series...

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Библиографические подробности
Опубликовано в: :Int J Mol Sci
Главные авторы: Milata, Viktor, Svedova, Alexandra, Barbierikova, Zuzana, Holubkova, Eva, Cipakova, Ingrid, Cholujova, Dana, Jakubikova, Jana, Panik, Miroslav, Jantova, Sona, Brezova, Vlasta, Cipak, Lubos
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6539820/
https://ncbi.nlm.nih.gov/pubmed/31052469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20092169
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