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Selective, pH‐Dependent Colorimetric and Fluorimetric Detection of Quadruplex DNA with 4‐Dimethylamino(phenyl)‐Substituted Berberine Derivatives

The 9‐ and 12‐dimethylaminophenyl‐substituted berberine derivatives 3 a and 3 b were readily synthesized by Suzuki‐Miyaura reactions and shown to be useful fluorescent probes for the optical detection of quadruplex DNA (G4‐DNA). Their association with the nucleic acids was investigated by spectromet...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Chemistry
Hauptverfasser: Wickhorst, Peter Jonas, Ihmels, Heiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8252107/
https://ncbi.nlm.nih.gov/pubmed/33855748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202100297
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