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Selective, pH‐Dependent Colorimetric and Fluorimetric Detection of Quadruplex DNA with 4‐Dimethylamino(phenyl)‐Substituted Berberine Derivatives

The 9‐ and 12‐dimethylaminophenyl‐substituted berberine derivatives 3 a and 3 b were readily synthesized by Suzuki‐Miyaura reactions and shown to be useful fluorescent probes for the optical detection of quadruplex DNA (G4‐DNA). Their association with the nucleic acids was investigated by spectromet...

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Bibliographic Details
Published in:Chemistry
Main Authors: Wickhorst, Peter Jonas, Ihmels, Heiko
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8252107/
https://ncbi.nlm.nih.gov/pubmed/33855748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202100297
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