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Effects of mutant huntingtin inactivation on Huntington disease‐related behaviours in the BACHD mouse model
AIMS: Huntington disease (HD) is a fatal neurodegenerative disorder with no disease‐modifying treatments approved so far. Ongoing clinical trials are attempting to reduce huntingtin (HTT) expression in the central nervous system (CNS) using different strategies. Yet, the distribution and timing of H...
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| Pubblicato in: | Neuropathol Appl Neurobiol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8247873/ https://ncbi.nlm.nih.gov/pubmed/33330988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12682 |
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