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Effects of mutant huntingtin inactivation on Huntington disease‐related behaviours in the BACHD mouse model

AIMS: Huntington disease (HD) is a fatal neurodegenerative disorder with no disease‐modifying treatments approved so far. Ongoing clinical trials are attempting to reduce huntingtin (HTT) expression in the central nervous system (CNS) using different strategies. Yet, the distribution and timing of H...

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Dades bibliogràfiques
Publicat a:Neuropathol Appl Neurobiol
Autors principals: Cheong, Rachel Y., Baldo, Barbara, Sajjad, Muhammad U., Kirik, Deniz, Petersén, Åsa
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247873/
https://ncbi.nlm.nih.gov/pubmed/33330988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12682
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