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Effects of mutant huntingtin inactivation on Huntington disease‐related behaviours in the BACHD mouse model

AIMS: Huntington disease (HD) is a fatal neurodegenerative disorder with no disease‐modifying treatments approved so far. Ongoing clinical trials are attempting to reduce huntingtin (HTT) expression in the central nervous system (CNS) using different strategies. Yet, the distribution and timing of H...

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書誌詳細
出版年:Neuropathol Appl Neurobiol
主要な著者: Cheong, Rachel Y., Baldo, Barbara, Sajjad, Muhammad U., Kirik, Deniz, Petersén, Åsa
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247873/
https://ncbi.nlm.nih.gov/pubmed/33330988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12682
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