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Effects of mutant huntingtin inactivation on Huntington disease‐related behaviours in the BACHD mouse model
AIMS: Huntington disease (HD) is a fatal neurodegenerative disorder with no disease‐modifying treatments approved so far. Ongoing clinical trials are attempting to reduce huntingtin (HTT) expression in the central nervous system (CNS) using different strategies. Yet, the distribution and timing of H...
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| 出版年: | Neuropathol Appl Neurobiol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2021
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8247873/ https://ncbi.nlm.nih.gov/pubmed/33330988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12682 |
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