Effects of mutant huntingtin inactivation on Huntington disease‐related behaviours in the BACHD mouse model

AIMS: Huntington disease (HD) is a fatal neurodegenerative disorder with no disease‐modifying treatments approved so far. Ongoing clinical trials are attempting to reduce huntingtin (HTT) expression in the central nervous system (CNS) using different strategies. Yet, the distribution and timing of H...

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Bibliographic Details
Published in:Neuropathol Appl Neurobiol
Main Authors: Cheong, Rachel Y., Baldo, Barbara, Sajjad, Muhammad U., Kirik, Deniz, Petersén, Åsa
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2021
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247873/
https://ncbi.nlm.nih.gov/pubmed/33330988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12682
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